in each reaction box place the best reagent and conditions from the list below. alkyne
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Question “in each reaction box place the best reagent and conditions from the list below. alkyne”
In each reaction box, place the best reagent and conditions from the list below. If you reduce the alkyne in step 3, you would need six steps overall to produce the final carboxylic acid.
Answer
General guidance
* A chemical reaction is a combination of several substances to create a product. Reagents are essential for most chemical reactions.
* Reagents can be substances that transform one substance into another.
* To obtain a final product, the reaction involves a number of steps, including substitution and deprotonation.
Reagents are crucial in every reaction. Each reagent has a unique role in the chemical reaction.
Deprotonation alkynes
With the aid of the reagent sodiumamide\\left( {{\\rm{NaN}}{{\\rm{H}}_{\\rm{2}}}} \\right), an alkyne undergoes its deprotonation
Substitution:
The nucleophilic substitution reaction $math_tag_1
Hydroboration alkenes
Borane in THF is a reagent which is used for the hydroboration of alkenes to give alkyl borane (organoboron) which is treated with \\[\\user2H_\\user22\\user2O_\\user22\\user2, O\\user2H^\\user2 – \\] forms alcohol.
Aldehydes oxidation:
Aldehydes are oxidized to carboxylic acids using a suitable reagent such as, \\[\\user2Cr\\user2O_\\user23\\user2, \\user2H_\\user22\\user2S\\user2O_\\user24\\user2 \\& \\user2H_\\user22\\user2O\\].
Step-by-step
Step 1 from 4
Step 2 from 4
Step 3 from 4
Common mistakes
The reaction begins with a concerted side addition of
to the carbon-carbon triple bonds in the synthetic intermediate product. \\[\\user2B\\user2H_\\user22\\] adds to the carbon with more number of hydrogens, while H adds to the carbon with less number of hydrogen. \\[\\user2B\\user2H_\\user23\\] acts as an electrophile because the boron having an empty p orbital makes it an electron deficient species. Aldehyde is formed by the second step of the oxidation. It follows the anti-Markovnikov\u2019s rule.
Step 4 from 4
The target product is obtained by using \\[\\user2Cr\\user2O_\\user23\\user2, \\user2H_\\user22\\user2S\\user2O_\\user24\\user2 \\& \\user2H_\\user22\\user2O\\] reagents on the synthetic intermediate product 3. This reaction is called oxidation reaction.
Answer
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Conclusion
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