Rank substituents in order of their priority when assigning the E or Z label to an…
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Question “Rank substituents in order of their priority when assigning the E or Z label to an…”
or Z label to an alkene.
I, CH2I , H, CH2CH2Cl, F
Answer
The E-Z system is the system that specifies configuration. It is based on the Cahn–Ingold-Prelog convention. Sequence rules are used to determine the relative priorities of the groups attached to the
double bond carbon atom. This process is repeated for the determination of relative priorities of two groups on the
double bond carbon atoms. The relative position of the groups of higher priority on each carbon atom is determined by the position of their respective groups on the other carbon. The isomer will have Z configuration if two groups with higher priority are located on the same side. If the two higher priority groups are located on opposite sides, the isomer will have E configuration.
Sequence rules: These rules determine the priority of the groups attached each
carbon double bond.
1.The higher priority of the group it is a member of, the greater the atomic numbers of any atom attached directly to the
carbon. The priority is given to the heavier isotopes if they are different atoms.
2.If rule 1 fails in determining the relative priority of two groups attached to a carbon, because the first two atoms in both groups are identical, then rule 2 may be applied. This is done by comparing the numbers of the next atoms in the groups.
3. Multiple bonds that are present are considered separate singles within the atoms.
=53
= 1.
= 9.
is the atom with highest atomic number.
is the highest priority atom.
is used to assign priority to substituents. If the two groups attached to a carbon are identical since the first two atoms, then the rule can be applied by comparing their atomic numbers.
A higher priority is given to an atom with a higher number of atomic numbers.
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